Income Taxes - Summary of Reconciliation of Statutory Income Tax Rate To Effective Income Tax Rate (Details) - USD ($) $ in Thousands		12 Months Ended
		Dec. 31, 2025	Dec. 31, 2024
Effective Income Tax Rate Reconciliation, Percent [Abstract]
Federal statutory tax rate, Amount		$ (46,175)	$ (35,313)
State and local income taxes, net of federal income tax effect, Amount	[1]	0	2,132
Research and development credits, Amount		(3,342)	(3,700)
Nontaxable or nondeductible items, Other, Amount		2,174	1,427
Other adjustments, Amount		13,870	2,130
Valuation allowance, Amount		33,473	33,441
Effective tax rate		$ 0	$ 117
Federal statutory rate		21.00%	21.00%
State taxes, net of federal benefit	[1]	0.00%	(1.27%)
Research and development credits		1.52%	2.20%
Nontaxable or nondeductible items, Other		(0.99%)	(0.85%)
Other adjustments		(6.31%)	(1.26%)
Valuation allowance		(15.22%)	(19.89%)
Effective tax rate		0.00%	(0.07%)

[1] Massachusetts makes up the majority (greater than 50 percent) of the State taxes, net of federal benefit category.