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Sale of Cullinan Pearl (Additional Information) (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Defined Benefit Plan Disclosure [Line Items]    
Research and development costs $ 187,402 $ 142,903
Pearl - Taiho    
Defined Benefit Plan Disclosure [Line Items]    
Percentage of profits from potential sales 50.00%