License and Collaboration Agreements - Additional Information (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2025	Mar. 31, 2024	Dec. 31, 2024
License And Collaboration Agreements [Line Items]
Research and development costs	$ 41,459	$ 30,646
General and administrative expense	$ 13,537	12,343
Pearl - Taiho
License And Collaboration Agreements [Line Items]
Percentage of profits from potential sales	50.00%
Research and development expense related to share of costs	$ 5,600	6,000
Accrued expenses and other current liabilities	4,700		$ 6,000
RecievablesFromRelatedParty	130,000
Research and development costs	1,400	$ 1,900
General and administrative expense	$ 500