Sale of Cullinan Pearl and Co-Development Agreement with Taiho (Additional Information) (Details) - USD ($) $ in Thousands	1 Months Ended	12 Months Ended
Jun. 30, 2022	Dec. 31, 2022	Dec. 31, 2021
Defined Benefit Plan Disclosure [Line Items]
Cash transferred with sale		$ 2,898
Gain on sale of Cullinan Pearl		276,785	$ 0
Repayment of convertible note		2,200	0
Research and development costs		91,948	$ 57,751
Prepaid expenses and other current assets		619
Pearl - Taiho
Defined Benefit Plan Disclosure [Line Items]
Receive upfront payment from party	$ 275,000
Cash transferred with sale	2,900
Additional receive payments from the party	130,000
Gain on sale of Cullinan Pearl	$ 276,800
Repayment of convertible note		2,200
Percentage of profits from potential sales	50.00%
Research and development costs		3,500
Research and development expense related to share of costs		2,500
Prepaid expenses and other current assets		$ 1,000

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