Sale of Cullinan Pearl and Co-Development Agreement with Taiho - Additional Information (Details) - USD ($) $ in Thousands	1 Months Ended	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Defined Benefit Plan Disclosure [Line Items]
Repayment of convertible notes				$ 2,200	$ 0
net of cash transferred				2,898
Gain on sale of Cullinan Pearl		$ (276,785)	$ 0	(276,785)	$ 0
Payment held in escrow				5,000
Pearl - Taiho
Defined Benefit Plan Disclosure [Line Items]
Repayment of convertible notes				2,200
net of cash transferred	$ 2,900
Additional receive payments from the party	130,000
Receive upfront payment from party	$ 275,000
Gain on sale of Cullinan Pearl		$ (276,800)		(276,800)
Payment held in escrow				$ 5,000
Percentage of profits from potential sales	50.00%