<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <!-- Field: Pseudo-Tag; ID: Name; Data: UZIEL AMIR -->
          <cik>0001310283</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>


    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <securitiesClassTitle>Common Stock, $0.0001 par value per share</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>02/20/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001789192</issuerCik>
        <issuerName>N2OFF, Inc.</issuerName>
        <issuerCusip>80512Q302</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>HaPardes 134 (Meshek Sander)</com:street1>
          <com:city>Neve Yarak</com:city>
          <com:stateOrCountry>L3</com:stateOrCountry>
          <com:zipCode>4994500</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Amir Uziel</reportingPersonName>
      <memberGroup>b</memberGroup>
      <citizenshipOrOrganization>L3</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>14286.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>14286.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>1565357.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>9.99</classPercent>
      <typeOfReportingPerson>IN</typeOfReportingPerson>
      <comments>(1) Amir Uziel is the officer, sole director, chairman of the board of directors and control shareholder of Uziel Economic Consultant.

(2) Mr. Uziel is the beneficial owner of 1,565,357 shares of Common Stock consisting of (a) 14,286 shares of Common Stock are held directly by Mr. Uziel, (b) 1,075,000 shares of Common Stock held by Uziel Economic Consultant, and (c) 476,071 shares of Common Stock issuable upon exercise of the Warrants held by Uziel Economic Consultant, which are exercisable within 60 days of the date hereof, which exercise is subject to the 9.99% Blocker.

(3) Based on 15,335,618 shares of Common Stock issued and outstanding, according to information provided by the Issuer.</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Amir Uziel Economic Consultant Ltd.</reportingPersonName>
      <memberGroup>b</memberGroup>
      <citizenshipOrOrganization>L3</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>1075000.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>1075000.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>1551071.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>9.81</classPercent>
      <typeOfReportingPerson>CO</typeOfReportingPerson>
      <comments>(1) Amir Uziel is the officer, sole director, chairman of the board of directors and control shareholder of Amir Uziel Economic Consultant Ltd. ("Uziel Economic Consultant").

(2) Uziel Economic Consultant is the beneficial owner of (a) 1,075,000 shares of N2OFF, Inc.'s (the "Issuer") common stock, par value $0.0001 per share (the "Common Stock"), and (b) 476,071 shares of Common Stock issuable upon exercise of warrants purchased by Uziel Economic Consultant on December 24, 2024 (the "Warrants"), which are exercisable within 60 days of the date hereof. Uziel Economic Consultant is prohibited from exercising the Warrants into Common Stock if, as a result of such exercise, the holder, together with its affiliates and any persons acting as a group together with such holder or any of such affiliates, would beneficially own more than 9.99% of the total number of Common Stock then issued and outstanding immediately after giving effect to the exercise (the "9.99% Blocker").

(3) Based on 15,335,618 shares of Common Stock issued and outstanding, according to information provided by the Issuer.</comments>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>N2OFF, Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>HaPardes 134 (Meshek Sander), Neve Yarak, Israel, 4994500</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>Amir Uziel</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>20 Raoul Wallenberg Suite 1001 Tel Aviv Israel</principalBusinessOfficeOrResidenceAddress>
        <citizenship>Israel</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>See items 5-11 of the cover pages hereto for beneficial ownership, percentage of class and dispositive power of the Reporting Person, which is incorporated herein.</amountBeneficiallyOwned>
        <classPercent>See items 5-11 of the cover pages hereto for beneficial ownership, percentage of class and dispositive power of the Reporting Person, which is incorporated herein.</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>See items 5-11 of the cover pages hereto for beneficial ownership, percentage of class and dispositive power of the Reporting Person, which is incorporated herein.</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>See items 5-11 of the cover pages hereto for beneficial ownership, percentage of class and dispositive power of the Reporting Person, which is incorporated herein.</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>See items 5-11 of the cover pages hereto for beneficial ownership, percentage of class and dispositive power of the Reporting Person, which is incorporated herein.</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>See items 5-11 of the cover pages hereto for beneficial ownership, percentage of class and dispositive power of the Reporting Person, which is incorporated herein.</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>Amir Uziel</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Amir Uziel</signature>
        <title>Amir Uziel</title>
        <date>02/24/2024</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Amir Uziel Economic Consultant Ltd.</reportingPersonName>
      <signatureDetails>
        <signature>Amir Uziel Economic Consultant Ltd.</signature>
        <title>Amir Uziel, CEO</title>
        <date>02/24/2024</date>
      </signatureDetails>
    </signatureInformation>
  </formData>
</edgarSubmission>
