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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Cash flows from operating activities:      
Net loss $ (152,261) $ (149,333) $ (147,305)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation and amortization 5,480 4,622 3,265
Impairment of inventories 1,140 224 1,664
Fair value at issuance of Series A warrants 0 6,500 0
Change in fair value of warrant liabilities 1,486 182 (970)
Stock-based compensation 23,708 23,675 24,247
Amortization of right-of-use assets 3,463 3,108 2,882
Realized loss on available-for-sale securities 0 0 29
Amortization of premium and accretion of discount on available-for-sale securities, net (3,537) (2,973) 389
Other 563 0 0
Accounts receivable (559) 2,259 (546)
Inventories (1,111) 353 (2,552)
Other current assets (2,566) 279 3,634
Other noncurrent assets 318 (270) (3)
Accounts payable 1,835 (1,592) 1,287
Accrued liabilities 2,334 (6,415) 4,953
Accrued employee costs (260) 1,322 2,525
Lease liability (3,595) (3,097) (2,871)
Other current liabilities 16,649 2,330 (539)
Net cash used in operating activities (106,913) (118,826) (109,911)
Cash flows from investing activities:      
Purchase of property, plant, and equipment (including advance) (5,107) (6,104) (7,439)
Purchase of non-marketable equity investments 0 (5,000) 0
Purchase of available-for-sale securities (79,980) (152,364) (210,197)
Proceeds from maturities of available-for-sale securities 182,988 232,745 328,526
Net cash provided by investing activities 97,901 69,277 110,890
Cash flows from financing activities:      
Proceeds from issuance of stock in private placement 0 21,455 0
Transaction costs related to issuance of stock in private placement 0 (818) 0
Payments of taxes withheld on net settled vesting of restricted stock units (752) (199) (720)
Proceeds from exercise of stock options 81 238 350
Proceeds from exercise of warrants 0 0 1
Net cash (used in) provided by financing activities (671) 20,676 (369)
Net increase (decrease) in cash and cash equivalents (9,683) (28,873) 610
Beginning cash and cash equivalents 38,547 67,420 66,810
Ending cash and cash equivalents 28,864 38,547 67,420
Supplemental disclosures of cash flow information:      
Cash paid for interest 0 0 0
Cash paid for income taxes 165 0 0
Supplemental disclosure of noncash investing and financing activities:      
Unpaid property, plant and equipment purchases 835 90 79
Right-of-use asset obtained in exchange for lease liability $ 0 $ 2,995 $ 0