Segment Reporting (Tables)

9 Months Ended

Sep. 30, 2026

Segment Reporting [Abstract]

Summary of Reconciliation to Net Loss

A reconciliation to the net loss for the three and nine months ended September 30, 2026 and 2025 is included at the bottom of the table below.

	Three Months Ended September 30,						Nine Months Ended September 30,
	2026			2025			2026			2025
Segment expenses:
Personnel related expenses, excluding share-based compensation(1)		8,329			8,125		$	25,724		$	31,739
Facilities expenses		4,826			5,241			13,696			14,577
Direct external development program expenses		11,474			4,644			29,950			14,913
Other segment expenses(2)		7,327			4,406			19,707			15,420
Total segment expenses:		31,956			22,416			89,077			76,649
Segment loss		(31,956	)		(22,416	)		(89,077	)		(76,649	)
Reconciling items:
Depreciation and amortization		(2,056	)		(2,306	)		(7,128	)		(6,936	)
Share-based compensation		(1,765	)		(1,773	)		(5,528	)		(6,660	)
Impairment of property and equipment		—			—			(5,670	)		—
Impairment of right-of-use asset		—			(791	)		(2,378	)		(791	)
Interest income		2,245			3,852			7,621			12,198
Other income, net		206			1,719			634			2,163
Net loss	$	(33,326	)	$	(21,715	)	$	(101,526	)	$	(76,675	)

(1) Personnel related expenses include ($0.1) million and $5.0 million of severance and other benefits expense for the three and nine months ended September 30, 2025, respectively.

(2) Other segment items include consultants and contractor, lab supplies, and general business expenses.