Stockholders' Equity (Tables)

9 Months Ended

Sep. 30, 2026

Stockholders' Equity Note [Abstract]

Summary of Stock Option Activity

The following table summarizes the option activity under the 2020 Plan and 2015 Plan during the nine months ended September 30, 2026:

	Number of shares			Weighted average exercise price		Weighted average remaining contractual term (in years)		Aggregate Intrinsic Value (in thousands)
Outstanding at December 31, 2025		10,737,203		$	8.22		6.6	$	134
Granted		2,762,692			2.13
Exercised		(360,208	)		2.09
Forfeited		(2,480,279	)		12.73
Outstanding at September 30, 2026		10,659,408			5.80		7.4		3,201
Exercisable at September 30, 2026		5,844,730			8.37		6.3		1,053
Vested and expected to vest at September 30, 2026		10,659,408			5.80		7.4		3,201

Summary of Restricted Stock Unit Activity

The following table summarizes the restricted stock unit activity under the 2020 Plan during the nine months ended September 30, 2026:

	Number of shares			Weighted average grant date fair value per share		Weighted average remaining contractual term (in years)
Outstanding at December 31, 2025		648,959		$	4.34		1.2
Granted		585,547			1.93
Vested		(218,810	)		5.38
Forfeited		(97,046	)		2.55
Outstanding at September 30, 2026		918,650		$	2.75		1.5

Summary of Share-based Compensation Expense

Share-based compensation expense for the three and nine months ended September 30, 2026 and 2025 was as follows (in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2026		2025		2026		2025
Research and development	$	657	$	541	$	2,112	$	2,532
General and administrative		1,108		1,232		3,416		4,128
Total share-based compensation	$	1,765	$	1,773	$	5,528	$	6,660