Segment Reporting (Tables)

3 Months Ended

Mar. 31, 2026

Segment Reporting [Abstract]

Summary of Reconciliation to Net Loss

A reconciliation to the net loss for the three months ended March 31, 2026 and 2025 is included at the bottom of the table below.

	Three Months Ended March 31,
	2026			2025
Segment expenses:
Personnel related expenses, excluding share-based compensation(1)		8,767		$	15,896
Facilities expenses		4,393			4,565
Direct external development program expenses		7,479			5,420
Other segment expenses(2)		5,999			5,550
Total segment expenses:		26,638			31,431
Segment loss		(26,638	)		(31,431	)
Reconciling items:
Depreciation and amortization		(2,340	)		(2,299	)
Share-based compensation		(1,898	)		(2,834	)
Interest income		2,838			4,376
Other income, net		206			205
Net loss	$	(27,832	)	$	(31,983	)

(1) Personnel related expenses include $5.1 million of severance and other benefits expense for the three months ended March 31, 2025, respectively.

(2) Other segment items include consultants and contractor, lab supplies, and general business expenses.