Segment Reporting (Tables)

12 Months Ended

Dec. 31, 2024

Segment Reporting [Abstract]

Summary of Reconciliation to Net Loss

A reconciliation to the net loss for the years ended December 31, 2024 and 2023 is included at the bottom of the table below.

	December 31,
	2024			2023
Segment expenses:
Personnel related expenses, excluding share-based compensation	$	41,129		$	42,329
Facilities expenses		19,403			16,392
Direct external development program expenses		21,431			29,517
Other segment expenses (1)		20,348			16,244
Total segment expenses:		102,311			104,482
Segment loss		(102,311	)		(104,482	)
Reconciling items:
Depreciation and amortization		(9,152	)		(5,869	)
Share-based compensation		(16,731	)		(17,199	)
Impairment of ROU asset					(4,100	)
Interest income		19,317			14,107
Other income, net		87			42
Net loss	$	(108,790	)	$	(117,501	)

(1) Other segment items include consultants and contractor, lab supplies, and general business expenses.