CONDENSED STATEMENT OF CASH FLOWS (Unaudited) - USD ($)	3 Months Ended
	Mar. 31, 2024	Mar. 31, 2023
Cash flows from operating activities
Net loss	$ (29,518,000)	$ (30,815,000)
Adjustments to reconcile net loss to net cash used in operating activities:
Share-based compensation expense	4,368,000	4,746,000
Depreciation and amortization	2,255,000	797,000
Accretion and amortization of premiums and discounts on investments, net	(1,568,000)	(2,253,000)
Realized gain on investments	0	(34,000)
Non-cash lease expense	592,000	545,000
Changes in operating assets and liabilities:
Prepaid expenses and other assets	(428,000)	(406,000)
Operating lease liabilities	(1,164,000)	7,992,000
Accounts payable and accrued and other liabilities	(3,043,000)	(1,330,000)
Net cash used in operating activities	(28,506,000)	(20,758,000)
Cash flows from investing activities
Purchases of property and equipment	(175,000)	(4,823,000)
Purchases of investments	(40,040,000)	(84,288,000)
Maturities of investments	61,700,000	126,040,000
Net cash provided by investing activities	21,485,000	36,929,000
Cash flows from financing activities
Proceeds from stock option exercises	578,000	1,000
Proceeds from issuance of common stock and pre-funded warrants, net of underwriting fees	225,688,000
Net cash provided by financing activities	226,266,000	1,000
Net increase in cash and cash equivalents	219,245,000	16,172,000
Cash, cash equivalents, and restricted cash beginning of period	33,783,000	40,237,000
Cash, cash equivalents, and restricted cash end of period	253,028,000	56,409,000
Reconciliation of cash, cash equivalents and restricted cash to the balance sheet:
Cash and cash equivalents	250,285,000	53,666,000
Restricted cash	2,743,000	2,743,000
Total cash, cash equivalents and restricted cash	253,028,000	56,409,000
Supplemental disclosures of non-cash investing activities:
Stock issuance costs included in accrued and other current liabilities	615,000
Acquisitions of property and equipment in accounts payable and accrued and other current liabilities	$ 1,277,000	$ 3,761,000