Share-Based Compensation (Tables)

9 Months Ended

Sep. 30, 2023

Share-Based Payment Arrangement [Abstract]

Summary of Stock Option Activity

The following table summarizes the option activity under the 2020 Plan and 2015 Plan during the nine months ended September 30, 2023:

	Number of shares			Weighted- average exercise price		Weighted- average remaining contractual term (in years)
Outstanding at December 31, 2022		5,519,275		$	17.17		8.1
Granted		2,338,828			4.39
Exercised		(6,145	)		3.61
Forfeited		(724,509	)		16.18
Outstanding at September 30, 2023		7,127,449		$	13.09		8.0
Exercisable at September 30, 2023		3,257,376		$	16.28		7.0
Vested and expected to vest at September 30, 2023		7,127,449		$	13.09		8.0

Summary of Restricted Stock Unit Activity

The following table summarizes the restricted stock unit activity under the 2020 Plan during the nine months ended September 30, 2023:

	Number of shares			Weighted-average grant date fair value per share
Outstanding at December 31, 2022		356,728		$	12.66
Granted		503,639			5.57
Vested		(88,543	)		12.66
Forfeited		(76,714	)		7.79
Outstanding at September 30, 2023		695,110		$	8.06

Summary of Share-based Compensation Expense

Share-based compensation expense for the three and nine ended September 30, 2023 and 2022 was as follows (in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2023		2022		2023		2022
Research and development	$	2,077	$	1,947	$	6,283	$	5,404
General and administrative		2,214		2,443		7,404		6,995
Total share-based compensation	$	4,291	$	4,390	$	13,687	$	12,399