CONDENSED STATEMENT OF CASH FLOWS (Unaudited) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Cash flows from operating activities
Net loss	$ (52,910)	$ (40,908)
Adjustments to reconcile net loss to net cash used in operating activities:
Share-based compensation expense	8,009	7,037
Depreciation and amortization	1,243	667
Accretion and amortization of premiums and discounts on investments, net	1,110	1,576
Non-cash lease expense	2,019	231
Changes in operating assets and liabilities:
Prepaid expenses and other assets	3,282	(987)
Operating lease right-of-use assets	2,923
Operating lease liabilities	726
Accounts payable and accrued and other liabilities	(1,274)	285
Net cash used in operating activities	(34,872)	(32,099)
Cash flows from investing activities
Purchases of property and equipment	(4,399)	(2,411)
Purchases of short-term investments	(175,011)	(86,234)
Maturities of short-term investments	69,088	47,500
Net cash used in investing activities	(110,322)	(41,145)
Cash flows from financing activities
Proceeds from stock option exercises	413	1,012
Proceeds from secondary offering, net of issuance costs	215,611
Net cash provided by financing activities	216,024	1,012
Net increase (decrease) in cash and cash equivalents	70,830	(72,232)
Cash, cash equivalents, and restricted cash beginning of period	62,914	97,105
Cash, cash equivalents, and restricted cash end of period	133,744	24,873
Reconciliation of cash, cash equivalents and restricted cash to the balance sheet:
Cash and cash equivalents	131,646	24,421
Restricted cash	2,098	452
Total cash, cash equivalents and restricted cash	133,744	24,873
Supplemental disclosures of non-cash investing and financing activities:
Acquisitions of property and equipment	$ 926	$ 255