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Share-Based Compensation (Tables)
3 Months Ended
Mar. 31, 2022
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]  
Summary of Stock Option Activity

The following table summarizes the option activity under the 2020 Plan and 2015 Plan during the three months ended March 31, 2022:

 

 

Number of shares

 

 

Weighted-
average
exercise
price

 

 

Weighted-
average
remaining
contractual
term
(in years)

 

Outstanding at December 31, 2021

 

 

4,204,686

 

 

$

19.19

 

 

 

8.2

 

Granted

 

 

1,007,090

 

 

 

12.09

 

 

 

 

Exercised

 

 

(21,067

)

 

 

3.74

 

 

 

 

Forfeited

 

 

(120,342

)

 

 

23.45

 

 

 

 

Outstanding at March 31, 2022

 

 

5,070,367

 

 

$

17.74

 

 

 

8.2

 

Exercisable at March 31, 2022

 

 

1,784,571

 

 

$

15.17

 

 

 

7.5

 

Vested and expected to vest at March 31, 2022

 

 

5,070,367

 

 

$

17.74

 

 

 

8.2

 

Summary of Restricted Stock Unit Activity

The following table summarizes the restricted stock unit activity under the 2020 Plan during the three months ended March 31, 2022:

 

 

 

Number of shares

 

 

Weighted-average
grant date fair value per share

 

Outstanding at December 31, 2021

 

 

 

 

$

 

Granted

 

 

240,888

 

 

 

12.14

 

Forfeited

 

 

(11,470

)

 

 

12.14

 

Vested

 

 

 

 

 

 

Outstanding at March 31, 2022

 

 

229,418

 

 

$

12.14

 

Summary of Share-based Compensation Expense

Share-based compensation expense for the three months ended March 31, 2022 and 2021 was as follows (in thousands):

 

 

 

Three Months Ended
March 31,

 

 

 

2022

 

 

2021

 

Research and development

 

$

1,855

 

 

$

1,570

 

General and administrative

 

 

2,242

 

 

 

1,777

 

Total share-based compensation

 

$

4,097

 

 

$

3,347