Leases - Additional Information (Details) - USD ($) $ in Thousands	1 Months Ended					12 Months Ended
	Oct. 31, 2021	Jul. 31, 2021	Jan. 31, 2021	May 31, 2020	May 31, 2018	Dec. 31, 2021	Dec. 31, 2020
Lessee Lease Description [Line Items]
Weighted-average discount rate						9.20%
Operating lease not yet commenced minimum lease payments						$ 4,600	$ 99,600
Expects to pay base rent over the lease term		$ 99,600
Lessee, operating lease, term of contract		12 years
Monthly base rent		$ 600
Maximum monthly base rent after increase on annual basis		800
Cash received for tenant improvement allowances to be repaid		4,400
Lease liabilities						12,459
Right-of-use assets						11,678	$ 8,505
Maximum
Lessee Lease Description [Line Items]
Tenant improvement allowances yet to receive		$ 25,200
Lease liabilities						62,000
Right-of-use assets						62,000
Minimum
Lessee Lease Description [Line Items]
Lease liabilities						49,000
Right-of-use assets						49,000
Letter of Credit
Lessee Lease Description [Line Items]
Security deposit						$ 1,600
Third amendment
Lessee Lease Description [Line Items]
Operating lease, description						The lease amendment for this additional space commenced in April 2021 and expires in March 2024.
Lease expiration month and year			2024-03
Other Current Assets
Lessee Lease Description [Line Items]
Operating lease receivable						$ 800
Initial Lease Agreement
Lessee Lease Description [Line Items]
Operating lease, existence of option to extend	true			true
Lease term				8 years
Lease expiration year	2029			2029
Lessee option to extend description	The lease amendment of this additional space is anticipated to commence in April 2022 and expires in January 2029. The Company expects to pay base rent of approximately $4.6 million over the lease term. The lease amendment also includes this additional space in the Company’s option to extend the amended Initial Lease Agreement for an additional seven-year term.					The lease amendment also includes an extension of the lease term for the existing office and laboratory space beginning on May 1, 2020 and expiring in January 2029. The amendment to the Initial Lease Agreement also includes an option to extend the lease for an additional seven-year term.
Expects to pay base rent over the lease term	$ 4,600
Corporate Office and Laboratory Space
Lessee Lease Description [Line Items]
Weighted-average remaining lease term						6 years 8 months 12 days
Renewal term						7 years
Operating lease, existence of option to extend						true
Lease expiration year					2025
Corporate Office and Laboratory Space | Initial Lease Agreement
Lessee Lease Description [Line Items]
Renewal term				7 years
Operating lease, existence of option to extend					true
Lessee option to extend description						In April 2019, the Company executed the first amendment to the Initial Lease Agreement for additional corporate space, laboratory space and manufacturing capabilities and an extension to the lease term through April 2026.