SCHEDULE 13G/A 0000902664-23-005332 0001165408 XXXXXXXX LIVE 3 Common stock, par value $0.0001 per share 12/31/2024 0001787400 Nkarta, Inc. 65487U108 1150 VETERANS BOULEVARD SOUTH SAN FRANCISCO CA 94080 Rule 13d-1(b) Adage Capital Management, L.P. DE 0.00 0.00 0.00 0.00 0.00 N 0 IA PN Adage Capital Partners GP, L.L.C. DE 0.00 0.00 0.00 0.00 0.00 N 0 OO This Schedule 13G/A is being submitted under the CIK number of Adage Capital Partners GP, L.L.C. (CIK 0001165408) in order to gain access to the EDGAR system under the structured data requirements applicable to Schedule 13G filings (effective December 18, 2024) due to the fact that the original Schedule 13G was filed by Adage Capital Partners GP, L.L.C. (CIK 0001165408). Adage Capital Partners GP, L.L.C. is no longer the beneficial owner of securities held by ACP. Robert Atchinson X1 0.00 0.00 0.00 0.00 0.00 N 0 HC IN Phillip Gross X1 0.00 0.00 0.00 0.00 0.00 N 0 HC IN Nkarta, Inc. 1150 Veterans Boulevard South San Francisco, CA 94080 This statement is filed by: (i) Adage Capital Management, L.P., a Delaware limited partnership ("ACM"), as the investment manager of Adage Capital Partners, L.P., a Delaware limited partnership ("ACP"), with respect to the shares of common stock, $0.0001 par value per share ("Common Stock") of Nkarta, Inc., a Delaware corporation (the "Company") that were directly held by ACP; (ii) Robert Atchinson ("Mr. Atchinson"), as (1) managing member of Adage Capital Advisors, L.L.C., a limited liability company organized under the laws of the State of Delaware ("ACA"), managing member of Adage Capital Partners GP, L.L.C., a limited liability company organized under the laws of the State of Delaware ("ACPGP"), general partner of ACP and (2) managing member of Adage Capital Partners LLC, a Delaware limited liability company ("ACPLLC"), general partner of ACM, with respect to the shares of Common Stock that were directly held by ACP; and (iii) Phillip Gross ("Mr. Gross"), as (1) managing member of ACA, managing member of ACPGP and (2) managing member of ACPLLC, general partner of ACM, with respect to the shares of Common Stock that were directly held by ACP. The foregoing persons are hereinafter sometimes collectively referred to as the "Reporting Persons." Any disclosures herein with respect to persons other than the Reporting Persons are made on information and belief after making inquiry to the appropriate party. The address of the business office of each of the Reporting Persons is 200 Clarendon Street, 52nd Floor, Boston, Massachusetts 02116. ACM is a limited partnership organized under the laws of the State of Delaware. Messrs. Gross and Atchinson are citizens of the United States. N IA HC The information required by Item 4(a) is set forth in Row 9 of the cover page for each of the Reporting Persons and is incorporated herein by reference. 0 The information required by Item 4(c)(i) is set forth in Row 5 of the cover page for each of the Reporting Persons and is incorporated herein by reference. The information required by Item 4(c)(ii) is set forth in Row 6 of the cover page for each of the Reporting Persons and is incorporated herein by reference. The information required by Item 4(c)(iii) is set forth in Row 7 of the cover page for each of the Reporting Persons and is incorporated herein by reference. The information required by Item 4(c)(iv) is set forth in Row 8 of the cover page for each of the Reporting Persons and is incorporated herein by reference. N Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. Adage Capital Management, L.P. /s/ Robert Atchinson 02/12/2025 Adage Capital Partners GP, L.L.C. /s/ Robert Atchinson 02/12/2025 Robert Atchinson /s/ Robert Atchinson 02/12/2025 Phillip Gross /s/ Phillip Gross 02/12/2025