Statements of Stockholders' Equity - USD ($) $ in Thousands	Common stock	Additional paid-in capital	Accumulated other comprehensive income (loss)	Accumulated deficit	Total
Balance at Beginning of period at Dec. 31, 2020	$ 4	$ 475,617	$ (12)	$ (170,895)	$ 304,714
Balance at Beginning of period (in shares) at Dec. 31, 2020	45,614,807
Stockholders' equity
Vesting of early exercise option awards		45			45
Vesting of early exercise option awards (in shares)	211,865
Exercise of stock options and vesting of restricted stock units		229			229
Exercise of stock options and vesting of restricted stock units (in shares)	101,479
Issuance of shares in connection with employee stock purchase plan		505			505
Issuance of shares in connection with employee stock purchase plan (in shares)	38,348
Sale of common stock, net of issuance costs	$ 1	165,804			165,805
Sale of common stock, net of issuance costs (in shares)	8,050,000
Unrealized gain (loss) on marketable securities			45		45
Share-based compensation expense		25,116			25,116
Net loss				(134,232)	(134,232)
Balance at end of period at Sep. 30, 2021	$ 5	667,316	33	(305,127)	362,227
Balance at end of period (in shares) at Sep. 30, 2021	54,016,499
Balance at Beginning of period at Jun. 30, 2021	$ 5	660,457	19	(258,212)	402,269
Balance at Beginning of period (in shares) at Jun. 30, 2021	53,956,380
Stockholders' equity
Vesting of early exercise option awards (in shares)	19,373
Exercise of stock options and vesting of restricted stock units		44			44
Exercise of stock options and vesting of restricted stock units (in shares)	40,746
Unrealized gain (loss) on marketable securities			14		14
Share-based compensation expense		6,815			6,815
Net loss				(46,915)	(46,915)
Balance at end of period at Sep. 30, 2021	$ 5	667,316	33	(305,127)	362,227
Balance at end of period (in shares) at Sep. 30, 2021	54,016,499
Balance at Beginning of period at Dec. 31, 2021	$ 5	675,346	(413)	(356,281)	318,657
Balance at Beginning of period (in shares) at Dec. 31, 2021	54,244,996
Stockholders' equity
Exercise of stock options and vesting of restricted stock units		128			128
Exercise of stock options and vesting of restricted stock units (in shares)	146,056
Issuance of shares in connection with employee stock purchase plan		243			243
Issuance of shares in connection with employee stock purchase plan (in shares)	155,544
Unrealized gain (loss) on marketable securities			(1,055)		(1,055)
Share-based compensation expense		15,477			15,477
Net loss				(109,054)	(109,054)
Balance at end of period at Sep. 30, 2022	$ 5	691,194	(1,468)	(465,335)	224,396
Balance at end of period (in shares) at Sep. 30, 2022	54,546,596
Balance at Beginning of period at Jun. 30, 2022	$ 5	688,253	(1,578)	(438,634)	248,046
Balance at Beginning of period (in shares) at Jun. 30, 2022	54,463,235
Stockholders' equity
Exercise of stock options and vesting of restricted stock units		79			79
Exercise of stock options and vesting of restricted stock units (in shares)	83,361
Unrealized gain (loss) on marketable securities			110		110
Share-based compensation expense		2,862			2,862
Net loss				(26,701)	(26,701)
Balance at end of period at Sep. 30, 2022	$ 5	$ 691,194	$ (1,468)	$ (465,335)	$ 224,396
Balance at end of period (in shares) at Sep. 30, 2022	54,546,596