Leases (Details) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022 USD ($) item	Sep. 30, 2021 USD ($)	Sep. 30, 2022 USD ($) item	Sep. 30, 2021 USD ($)	Jan. 01, 2022 USD ($)	Dec. 31, 2021 USD ($)
Lessee, Lease, Description [Line Items]
Rent expense	$ 800	$ 800	$ 2,500	$ 2,500
Deferred rent					$ 3,200	$ 6,921
Tenant improvement allowances liability					3,800
Operating lease liability	27,289		27,289
Right-of-use assets	19,890		19,890
Future minimum lease payments
2022 (remaining)	845		845
2023	3,450		3,450			2,884
2024	3,548		3,548			3,453
2025	3,648		3,648			3,550
2026	3,751		3,751			3,651
2026						3,754
Thereafter						33,534
Thereafter	33,507		33,507
Total Undiscounted lease payments	48,749		48,749			$ 50,826
Less: imputed interest	(21,460)		(21,460)
Total Lease Liabilities	27,289		27,289
Other current assets
Lessee, Lease, Description [Line Items]
Tenant improvements	$ 100		$ 100
Accounting Standards Update 2016-02
Lessee, Lease, Description [Line Items]
Operating lease liability					27,300
Right-of-use assets					20,400
Future minimum lease payments
Total Lease Liabilities					$ 27,300
Operating Leases For Office Space
Lessee, Lease, Description [Line Items]
Incremental borrowing rate	9.00%		9.00%
Operating Leases For Laboratory Space
Lessee, Lease, Description [Line Items]
Incremental borrowing rate	10.00%		10.00%
Maximum | Operating Leases For Office Space
Lessee, Lease, Description [Line Items]
Number of extension terms | item	2		2
Extended term of new lease agreement			5 years
Tenant improvement allowance	$ 2,800		$ 2,800
Maximum | Operating Leases For Laboratory Space
Lessee, Lease, Description [Line Items]
Number of extension terms | item	2		2
Extended term of new lease agreement			5 years
Tenant improvement allowance	$ 1,300		$ 1,300