Commitments and Contingencies - Collaboration Agreements (Details) - USD ($) $ in Thousands	1 Months Ended	3 Months Ended		6 Months Ended
	Feb. 29, 2020	Jun. 30, 2026	Dec. 31, 2025	Jun. 30, 2026
Commitments and Contingencies
Non - Refundable aggregate fees payable		$ 1,000		$ 1,000
Non - Refundable upfront fees payable		500		500
Non - Refundable fees payable		500		500
Paid catalent fee		900	$ 900
Divestiture fee due to Catalent			$ 924
Amount of loss contingency		0		$ 0
Common stock	150,000
Loss contingency, shares agreed by defendant	33,836			1,692
Target annual bonus				150.00%
Amended and restated agreement
Commitments and Contingencies
Amount payable per product candidate for rare, monogenic disorders		16,500		$ 16,500
Sales milestone payments		55,000		55,000
Gemma License Agreement
Commitments and Contingencies
Amount payable per product candidate for rare, monogenic disorders		16,500		16,500
Amount payable per product candidate upon achievement of specific development milestone		39,000		39,000
Sales milestone payments		$ 55,000		$ 55,000