144 0001786304 XXXXXXXX LIVE 0001745999 BEAM THERAPEUTICS INC. 001-39208 238 Main Street Cambridge MA 02142 857-327-8775 JOHN M. EVANS Officer Director Common Stock ETRADE FINANCIAL CORPORATION

3 EDISON DRIVE ALPHARETTA GA 30005

66874 1464540.6 101856245 04/02/2026 NASDAQ Common Stock 03/31/2026 Restricted Stock Vesting Issuer N 66874 03/31/2026 Services Rendered N John M. Evans

238 Main Street Cambridge MA 02142

Common Stock 01/29/2026 25000 734582.50 John M. Evans

238 Main Street Cambridge MA 02142

Common Stock 01/30/2026 25000 708946.63 Represents shares of common stock sold in a non-discretionary transaction by the seller in order to cover tax withholding obligations upon the vesting of certain restricted stock units granted to the seller. 03/31/2026 05/19/2023 /s/John M. Evans