X0306 4 2022-02-10 0 0001786255 Icosavax, Inc. ICVX 0001874017 Cearley Cassia C/O ICOSAVAX, INC. 1616 EASTLAKE AVENUE E., SUITE 208 SEATTLE WA 98102 0 1 0 0 Chief Business Officer Common Stock 2022-02-10 4 A 0 21256 0.00 A 108413 D Stock Option (Right to Buy) 17.55 2022-02-10 4 A 0 89400 0.00 A 2032-02-09 Common Stock 89400 89400 D Represents restricted stock units ("RSUs") which will vest as to 25% of the total number of RSUs granted on each of the first four anniversaries of February 10, 2022, subject to the reporting persons continued service through the applicable vesting date. Each RSU represents a contingent right to receive one share of common stock of the Issuer and the RSUs have no expiration date. Includes 1,666 shares acquired under the Issuer's employee stock purchase plan on November 30, 2021. 25% of the shares subject to the option will vest on February 10, 2023, and 1/48th of the shares subject to the option vest monthly thereafter, subject to the reporting person's continued service through the applicable vesting date. Exhibit 24.1 - Power of Attorney /s/ Elizabeth Bekiroglu, Attorney-in-Fact for Cassia Cearley 2022-02-14