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Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Operating activities:    
Net loss and comprehensive loss $ (91,758) $ (66,971)
Adjustments to reconcile net loss to cash used in operating activities:    
Stock-based compensation 21,694 29,031
Depreciation 860 82
Non-cash lease expense 983 0
Amortization of premiums and discounts on short-term investments (1,528) 0
Non-cash interest expense 0 264
Change in fair value of embedded derivative liability 0 205
Loss on extinguishment of convertible promissory note 0 (754)
Changes in operating assets and liabilities:    
Prepaids and other current assets 1,284 (5,167)
Accounts payable (1,195) 1,839
Accrued and other current liabilities 4,002 3,225
Deferred revenue (582) (1,802)
Proceeds from lease incentive 4,565 0
Net cash used in operating activities (61,675) (38,540)
Investing activities:    
Purchases of property and equipment (11,113) (1,006)
Purchases of short-term investments (221,086) 0
Maturities of short-term investments 62,750 0
Net cash used in investing activities (169,449) (1,006)
Financing activities:    
Proceeds from issuance of convertible preferred stock, net of issuance costs 0 113,634
Proceeds from initial public offering, net of offering costs 0 190,738
Proceeds from issuance of common stock, net of issuance costs 9,413 0
Proceeds from exercise of stock options, including early exercise 894 400
Net cash provided by financing activities 10,307 304,772
Net increase (decrease) in cash, cash equivalents, and restricted cash (220,817) 265,226
Cash, cash equivalents, and restricted cash at beginning of period 280,724 15,498
Cash, cash equivalents, and restricted cash at end of period 59,907 280,724
Supplemental disclosure of noncash activities    
Conversion of preferred stock to common stock 0 151,613
Purchases of property and equipment included in accounts payable 330 142
Right-of-use assets and lease liabilities recognized upon commencement of lease $ 3,370 $ 0