Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Income Statement [Abstract]
Grant revenue	$ 582	$ 7,802
Research and development	65,410	38,776
General and administrative	30,230	34,887
Total operating expenses	95,640	73,663
Loss from operations	(95,058)	(65,861)
Change in fair value of embedded derivative liability	0	(205)
Loss on extinguishment of convertible promissory note	0	(754)
Interest and other	3,300	(151)
Total other expense	3,300	(1,110)
Net loss	(91,758)	(66,971)
Other comprehensive loss:
Unrealized losses on available-for-sale debt securities	(403)
Comprehensive loss	$ (92,161)	$ (66,971)
Net loss per share, basic	$ (2.31)	$ (3.73)
Net loss per share, diluted	$ (2.31)	$ (3.73)
Weighted-average common shares outstanding, basic and diluted	39,725,131	17,965,894
Weighted-average common shares outstanding, basic and diluted	39,725,131	17,965,894