Commitments - Additional Information (Details) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022	Dec. 31, 2022
Related Party Transaction [Line Items]
Finance lease liabilities, current	$ 38,045,000		$ 38,045,000		$ 33,060,000
Accrued liabilities	12,390,000		12,390,000		11,679,000
Accounts payable	5,693,000		$ 5,693,000		$ 9,053,000
Contracts cancelable period			30 days
Maximum development milestones receivable	28,800,000		$ 28,800,000
Maximum commercial milestones receivable	52,000,000.0		$ 52,000,000.0
Lonza
Related Party Transaction [Line Items]
Prior notification period to terminate arrangement			12 months
Minimum non-cancellable costs	58,700,000		$ 58,700,000
Finance lease liabilities, current	37,900,000		37,900,000
Accrued liabilities	2,700,000		2,700,000
Accounts payable	3,300,000		3,300,000
Payments for non-cancellable costs	$ 9,800,000	$ 2,800,000	$ 20,600,000	$ 10,900,000