Income Taxes - Schedule of Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Deferred income tax assets:
U.S. federal net operating loss carryforward	$ 33,398	$ 24,692
State net operating loss carryforward	10,465	7,592
Research and development expenditures	35,339
Research and development credits	1,935	3,218
Operating lease liabilities	9,876	570
Non-qualified stock options	6,802	1,665
Accrued bonus		941
Other	92	179
Gross deferred income tax assets	97,907	38,857
Less: Valuation allowance	(89,871)	(38,725)
Total deferred income tax assets	8,036	132
Deferred income tax liabilities:
Depreciation	(139)	(132)
Right-of-use asset - operating	(7,897)
Net deferred income tax assets (liabilities)	$ 0	$ 0