CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Cash flows from operating activities
Net loss	$ (188,679)	$ (64,969)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	1,321	1,041
Loss on disposal of property and equipment	3	3
Noncash operating lease expense	903
Right of use asset expensed	63,278
Amortization of premiums and discounts on marketable securities	(2,125)	210
Share-based compensation	21,544	6,754
Changes in operating assets and liabilities:
Prepaid expenses and other current and non-current assets	(5,695)	(6,059)
Accounts payable and other current liabilities	7,419	974
Accrued liabilities	(395)	7,764
Operating lease liabilities	3,123
Deferred rent		44
Net cash used in operating activities	(99,303)	(54,238)
Cash flows from investing activities
Purchases of property and equipment	(2,277)	(5,783)
Purchases of marketable securities	(273,737)	(74,193)
Proceeds from maturities of marketable securities	158,340
Net cash used in investing activities	(117,674)	(79,976)
Cash flows from financing activities
Proceeds from issuance of common stock (initial public offering), net of transactions costs	129,156
Proceeds from issuance of common stock (private placement), net of transactions costs	9,958
Proceeds from issuance of common stock (follow-on offering), net of transactions costs	120,719
Proceeds from issuance of Series C redeemable convertible preferred stock, net of transaction costs		119,118
Proceeds from exercise of stock options and early exercise of restricted stock	2,467	432
Payments for repurchase of restricted stock		(24)
Payments under finance leases	(9,675)
Payments under capital leases		(387)
Payments of deferred offering costs		(688)
Net cash provided by financing activities	252,625	118,451
Net increase in cash and cash equivalents and restricted cash	35,648	(15,763)
Cash and cash equivalents and restricted cash, beginning of the year	31,032	46,795
Cash and cash equivalents and restricted cash, end of the period	66,680	31,032
Supplemental disclosures of noncash investing and financing activities:
Purchase of property and equipment included in accounts payable and accrued liabilities	$ 770	278
Deferred offering costs included in accounts payable and accrued liabilities		$ 1,301