Commitments and Contingencies - Additional Information (Details) - USD ($)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Related Party Transaction [Line Items]
Finance lease liabilities, current	$ 33,060,000
Accounts payable	$ 9,053,000	$ 1,333,000
Contracts cancelable period	30 days
Maximum development milestones receivable	$ 28,800,000
Maximum commercial milestones receivable	$ 52,000,000.0
Lonza
Related Party Transaction [Line Items]
Prior notification period to terminate arrangement	12 months
Minimum non-cancellable costs	$ 58,200,000
Finance lease liabilities, current	32,900,000
Accounts payable	3,300,000
Payments for non-cancellable costs	$ 16,100,000