Nature of the Business and Basis of Presentation - Schedule of Effect of Restatement on Company's Unaudited Condensed Consolidated Financial Statements (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2021	Dec. 31, 2020
Changes in the balance sheet:
Prepaid expenses and other current assets	$ 13,460		$ 8,192
Total current assets	224,389		112,809
Property and equipment, net	9,747		10,318
Prepaid research and development expenses and other long-term assets	9,401		2,284
Total assets	246,984		128,782
Accrued liabilities	11,650		13,180
Operating lease liabilities, current portion	737
Total current liabilities	14,425		14,845
Operating lease liabilities, net of current portion	4,477
Total liabilities	19,049		16,918
Accumulated Deficit	(156,152)		(130,111)
Total stockholders' equity	227,935	$ (74,232)	(121,515)	$ (63,720)
Total liabilities and stockholders' equity	246,984		$ 128,782
Changes in the statement of operations and comprehensive loss:
Research and development	18,057	8,521
Total operating expenses	26,091	11,282
Loss from operations	(26,091)	(11,282)
Net loss	(26,041)	(11,281)
Comprehensive loss	$ (26,065)	$ (11,281)
Net loss per share attributable to common stockholders - basic	$ (1.25)	$ (33.45)
Net loss per share attributable to common stockholders - diluted	$ (1.25)	$ (33.45)
Changes in the statement of cash flows:
Net loss	$ (26,041)	$ (11,281)
Depreciation and amortization	263	207
Prepaid expenses and other current and non-current assets	(11,864)	48
Accrued liabilities	(187)	392
Net cash used in operating activities	(32,586)	$ (9,507)
Previously Reported [Member]
Changes in the balance sheet:
Prepaid expenses and other current assets	9,974
Total current assets	220,903
Property and equipment, net	10,127
Prepaid research and development expenses and other long-term assets	8,913
Total assets	243,390
Accrued liabilities	14,400
Operating lease liabilities, current portion	370
Total current liabilities	16,808
Operating lease liabilities, net of current portion	4,844
Total liabilities	21,799
Accumulated Deficit	(162,496)
Total stockholders' equity	221,591
Total liabilities and stockholders' equity	243,390
Changes in the statement of operations and comprehensive loss:
Research and development	24,401
Total operating expenses	32,435
Loss from operations	(32,435)
Net loss	(32,385)
Comprehensive loss	$ (32,409)
Net loss per share attributable to common stockholders - basic	$ (1.56)
Net loss per share attributable to common stockholders - diluted	$ (1.56)
Changes in the statement of cash flows:
Net loss	$ (32,385)
Depreciation and amortization	416
Prepaid expenses and other current and non-current assets	(8,423)
Accrued liabilities	2,563
Net cash used in operating activities	(32,586)
Correction of Error
Changes in the balance sheet:
Prepaid expenses and other current assets	3,486
Total current assets	3,486
Property and equipment, net	(380)
Prepaid research and development expenses and other long-term assets	488
Total assets	3,594
Accrued liabilities	(2,750)
Operating lease liabilities, current portion	367
Total current liabilities	(2,383)
Operating lease liabilities, net of current portion	(367)
Total liabilities	(2,750)
Accumulated Deficit	6,344
Total stockholders' equity	6,344
Total liabilities and stockholders' equity	3,594
Changes in the statement of operations and comprehensive loss:
Research and development	(6,344)
Total operating expenses	(6,344)
Loss from operations	6,344
Net loss	6,344
Comprehensive loss	$ 6,344
Net loss per share attributable to common stockholders - basic	$ 0.31
Net loss per share attributable to common stockholders - diluted	$ 0.31
Changes in the statement of cash flows:
Net loss	$ 6,344
Depreciation and amortization	(153)
Prepaid expenses and other current and non-current assets	(3,441)
Accrued liabilities	$ (2,750)