X0306 4 2021-05-04 1 0001785530 Werewolf Therapeutics, Inc. HOWL 0001762853 Longwood Fund III GP, LLC 800 BOYLSTON STREET SUITE 1555 BOSTON MA 02199 0 0 1 0 0001640546 Longwood Fund III, L.P. 800 BOYLSTON STREET SUITE 1555 BOSTON MA 02199 0 0 1 0 Common Stock 2021-05-04 4 C 0 1071127 A 1071127 I See footnote Common Stock 2021-05-04 4 C 0 355955 A 1427082 I See footnote Common Stock 2021-05-04 4 P 0 250000 16.00 A 1677082 I See footnote Series A Preferred Stock 2021-05-04 4 C 0 9285714 0.00 D Common Stock 1071127 0 I See footnote Series B Preferred Stock 2021-05-04 4 C 0 3085811 0.00 D Common Stock 355955 0 I See footnote On May 4, 2021, the Series A Preferred Stock automatically converted into Common Stock on a 8.6691-for-one basis without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date. These securities are held of record by Longwood Fund III, L.P. ("Longwood III"). Longwood Fund III GP, LLC ("Longwood III GP") is the general partner of Longwood III. Voting, investment and dispositive decisions at Longwood III GP with respect to the securities held by Longwood III are made by an investment committee comprised of Christoph Westphal, Richard Aldrich and John Lawrence (collectively, the "IC Members"). Longwood III GP and each of the IC Members may be deemed to share voting, investment and dispositive power over the securities held by Longwood III and as a result may be deemed to have beneficial ownership over such securities. Longwood III GP and each of the IC Members disclaims beneficial ownership over the securities held by Longwood III, except to the extent of their respective pecuniary interests therein. On May 4, 2021, the Series B Preferred Stock automatically converted into Common Stock on a 8.6691-for-one basis without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date. By: /s/ John Lawrence, Chief Financial Officer of Longwood Fund III GP, LLC 2021-05-04 By: /s/ John Lawrence, Chief Financial Officer of Longwood Fund III GP, LLC, the general partner of Longwood Fund III, L.P. 2021-05-04