X0206 3 2021-04-29 0 0001785530 Werewolf Therapeutics, Inc. HOWL 0001654430 Morrison Briggs C/O WEREWOLF THERAPEUTICS, INC. 1030 MASSACHUSETTS AVENUE, SUITE 210 CAMBRIDGE MA 02138 1 0 0 0 Common Stock 15523 D Stock Option (right to buy) 1.56 2029-12-12 Common Stock 31047 D The option was granted on December 13, 2019 with a Vesting Commencement date of November 13, 2019. The shares underlying the option vest over four years in equal monthly installments through November 13, 2023. Exhibit Index: 24.1 Power of Attorney /s/ Reid Leonard, Attorney-in-fact 2021-04-29