X0206 3 2021-04-29 0 0001785530 Werewolf Therapeutics, Inc. HOWL 0001857799 Seidel-Dugan Cynthia C/O WEREWOLF THERAPEUTICS, INC. 1030 MASSACHUSETTS AVENUE, SUITE 210 CAMBRIDGE MA 02138 0 1 0 0 Chief Scientific Officer Common Stock 125157 D Stock Option (right to buy) 1.56 2030-05-19 Common Stock 61136 D Stock Option (right to buy) 4.77 2030-12-07 Common Stock 99163 D The option was granted on May 20, 2020 with a Vesting Commencement Date of June 1, 2020. The shares underlying the option vest over four years, with 25% of the shares vesting on the first anniversary of the Vesting Commencement Date and 2.0833% of the shares vesting each month thereafter through June 1, 2024. The option was granted on December 8, 2020. The shares underlying the option vest over four years, with 25% of the shares vesting on the first anniversary of the grant date and 2.0833% of the shares vesting each month thereafter through December 8, 2024. Exhibit Index: 24.1 Power of Attorney /s/ Reid Leonard, Attorney-in-fact 2021-04-29