Consolidated Statements of Stockholders' Equity (Deficit) - USD ($) $ in Thousands	Total	A T M Facility	Public Offerings	Common Stock	Common Stock A T M Facility	Common Stock Public Offerings	Additional Paid-in Capital	Additional Paid-in Capital A T M Facility	Additional Paid-in Capital Public Offerings	Accumulated Other Comprehensive Loss	Accumulated Other Comprehensive Loss A T M Facility	Accumulated Other Comprehensive Loss Public Offerings	Retained Earnings
Beginning balance at Dec. 31, 2019	$ 89,944			$ 14			$ 163,526			$ 0			$ (73,596)
Beginning balance, shares at Dec. 31, 2019				13,788,982
Issuance of common stock			$ 157,680			$ 6			$ 157,674			$ 0
Issuance of common stock, shares						6,072,040
Issuance of common stock upon exercise of stock options	271						271			0
Issuance of common stock upon exercise of stock options, shares				63,366
Issuance of common stock upon ESPP purchase	134						134			0
Issuance of common stock upon ESPP purchase, Shares				7,272
Issuance of common stock warrant in connection with term loan facility	634						634			0
Stock-based compensation	3,807						3,807			0
Issuance Of Common Stock Warrants In Connection With Debt Financing										0
Net loss	(49,499)									0			(49,499)
Other comprehensive loss	(10)									(10)
Ending balance at Dec. 31, 2020	202,961			$ 20			326,046			(10)			(123,095)
Ending balance, shares at Dec. 31, 2020				19,931,660
Issuance of common stock		$ 3,289						$ 3,289			$ 0
Issuance of common stock, shares					186,546
Issuance of common stock upon exercise of stock options	487						487			0
Issuance of common stock upon exercise of stock options, shares				188,286
Issuance of common stock upon ESPP purchase	144						144			0
Issuance of common stock upon ESPP purchase, Shares				10,712
Issuance of common stock warrant in connection with term loan facility	574						574			0
Stock-based compensation	8,678						8,678			0
Net loss	(90,122)									0			(90,122)
Other comprehensive loss	(54)									(54)
Ending balance at Dec. 31, 2021	$ 125,957			$ 20			$ 339,218			$ (64)			$ (213,217)
Ending balance, shares at Dec. 31, 2021				20,317,204