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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Cash flows from operating activities:    
Net loss $ (71,275) $ (51,681)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 7,216 4,998
Net accretion of discounts on investments in marketable securities (1,898) (2,822)
Amortization of debt discount and accretion of deferred debt costs 455 162
Noncash operating lease expense 163 175
Depreciation 10 9
Change in fair value of warrant liability (221) 0
Changes in operating assets and liabilities:    
Prepaid expenses and other assets (7,869) 2,089
Accounts payable (600) 6,767
Accrued expenses 2,323 457
Operating lease liabilities (178) 29
Other noncurrent liabilities 137 97
Net cash used in operating activities (71,737) (39,720)
Cash flows from investing activities:    
Proceeds from sales and maturities of marketable securities 97,341 72,140
Purchases of marketable securities (105,102) (152,038)
Purchases of property and equipment (72) 0
Net cash used in investing activities (7,833) (79,898)
Cash flows from financing activities:    
Proceeds from issuance of common stock and pre-funded warrants in public offering, net of issuance costs 269,903 0
Payments of deferred offering costs 0 (253)
Proceeds from issuance of common stock in at-the-market public offerings, net of issuance costs 0 21,067
Proceeds from issuance of common stock upon exercise of common stock warrants 0 1,798
Proceeds from issuance of common stock upon exercise of stock options 33 104
Payments for taxes related to net share settlement upon vesting of restricted stock units (1,030) (1,686)
Net cash provided by financing activities 268,906 21,030
Net change in cash and cash equivalents 189,336 (98,588)
Cash and cash equivalents at beginning of period 126,060 316,161
Cash and cash equivalents at end of period 315,396 217,573
Supplemental disclosures of cash information:    
Cash paid for interest $ 814 $ 679