Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022
Cash flows from operating activities:
Net loss	$ (101,954)	$ (77,424)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation	12,069	7,598
Net accretion on available-for-sale securities	(4,297)	(183)
Accretion of final payment fee on term loan	285	365
Amortization of debt issuance costs	410	227
Loss on extinguishment of term loan facility	1,208
Noncash operating lease expense	125	135
Depreciation	34	50
Changes in operating assets and liabilities:
Prepaid and other current assets	(3,238)	4,756
Other assets		72
Accounts payable	(1,599)	7,308
Accrued expenses	2,189	3,243
Operating lease liability	(125)	(141)
Net cash used in operating activities	(94,893)	(53,994)
Cash flows from investing activities:
Proceeds from sales and maturities of available-for-sale securities	157,428	87,260
Purchases of available-for-sale securities	(216,804)	(110,137)
Purchases of property and equipment		(5)
Net cash used in investing activities	(59,376)	(22,882)
Cash flows from financing activities:
Proceeds from issuance of common stock in public offering, net of issuance costs	296,817	88,239
Proceeds from issuance of common stock in at-the-market public offering, net of issuance costs	37,089	8,370
Proceeds from term loan facility, net of issuance costs	24,363
Proceeds from issuance of common stock upon exercise of warrants	15,590	53
Proceeds from issuance of common stock upon exercise of stock options	629	237
Proceeds from issuance of common stock upon ESPP purchases	142	43
Payment of withholding taxes related to restricted stock units	(2,290)	(122)
Repayment of term loan facility	(21,400)
Net cash provided by financing activities	350,940	96,820
Net change in cash and cash equivalents, and restricted cash	196,671	19,944
Cash and cash equivalents, and restricted cash at beginning of period	55,255	52,457
Cash and cash equivalents at end of period	251,926	72,401
Supplemental disclosures of cash information:
Cash paid for interest	1,913	706
Cash paid for operating leases	139	187
Supplemental disclosures of noncash information:
Issuance of common stock warrants in connection with term loan	$ 482
Remeasurement of lease liability and right of use asset in connection with lease modification		$ 338