X0206 3 2019-11-08 0 0001785173 89bio, Inc. ETNB 0001568077 Kariv Tomer 14 SHENKAR STREET, BEIT OFEK HERZLIYA PITUACH L3 L3 46140 ISRAEL 1 0 1 0 0001792890 Pontifax (Israel) V, L.P. 14 SHENKAR STREET, BEIT OFEK HERZLIYA PITUACH L3 L3 46140 ISRAEL 0 0 1 0 0001792893 Pontifax (Cayman) V, L.P. 14 SHENKAR STREET, BEIT OFEK HERZLIYA PITUACH L3 L3 46140 ISRAEL 0 0 1 0 0001792891 Pontifax (China) V, L.P. 14 SHENKAR STREET, BEIT OFEK HERZLIYA PITUACH L3 L3 46140 ISRAEL 0 0 1 0 0001792892 Pontifax 5 G.P. L.P. 14 SHENKAR STREET, BEIT OFEK HERZLIYA PITUACH L3 L3 46140 ISRAEL 0 0 1 0 0001726334 Pontifax Management 4 G.P. (2015) Ltd. 14 SHENKAR STREET, BEIT OFEK HERZLIYA PITUACH L3 L3 46140 ISRAEL 0 0 1 0 Series A Preferred Stock Common Stock 884671 I See footnote Each share of Series A Preferred Stock is convertible into common stock on a one-for-6.217 basis into the number of shares of common stock shown in column 3 at any time at the holder's election and automatically immediately prior to the closing of the Issuer's initial public offering. The Series A Preferred Stock has no expiration date. Includes (a) 3,322,005 shares held by Pontifax (Israel) V, L.P., (b) 887,328 shares held by Pontifax (Cayman) V, L.P. and (c) 1,290,668 shares held by Pontifax (China) V, L.P. (collectively, the "Pontifax Entities"). Pontifax 5 G.P. L.P. ("Pontifax 5 GP") is the general partner of each of the Pontifax Entities, and Pontifax Management 4 G.P. (2015) Ltd. ("Pontifax Management") is the general partner of Pontifax 5 GP. Mr. Tomer Kariv is one of two Managing Partners of Pontifax Management and, as a result, may be deemed to share voting and investment power with respect to the shares held by each of the Pontifax Entities. Mr. Kariv disclaims beneficial ownership of those shares held by the Pontifax Entities, except to the extent of his pecuniary interest therein. /s/ Tomer Kariv 2019-11-08 Pontifax (Israel) V, L.P.; By /s/ Tomer Kariv, Chief Executive Officer 2019-11-08 Pontifax (Cayman) V, L.P.; By /s/ Tomer Kariv, Chief Executive Officer 2019-11-08 Pontifax (China) V, L.P.; By /s/ Tomer Kariv, Chief Executive Officer 2019-11-08 Pontifax 5 G.P. L.P.; By /s/ Tomer Kariv, Chief Executive Officer 2019-11-08 Pontifax Management 4 G.P. (2015) Ltd.; By /s/ Tomer Kariv, Chief Executive Officer 2019-11-08