X0206 3 2019-11-08 0 0001785173 89bio, Inc. ETNB 0001352908 Hayden Michael R C/O 89BIO, INC. 535 MISSION STREET, 14TH FLOOR SAN FRANCISCO CA 94105 1 0 0 0 Series A Preferred Stock Common Stock 58978 I See footnote Stock Option (Right to Buy) 1.93 2028-11-09 Common Stock 88467 D Stock Option (Right to Buy) 1.93 2029-01-30 Common Stock 9380 D Stock Option (Right to Buy) 3.11 2029-07-30 Common Stock 36367 D Each share of Series A Preferred Stock is convertible into common stock on a one-for-6.217 basis into the number of shares of common stock shown in column 3 at any time at the holder's election and automatically immediately prior to the closing of the Issuer's initial public offering. The Series A Preferred Stock has no expiration date. These shares are held directly by Genworks 2 Consulting Inc., over which the Reporting Person's wife has sole voting and investment power. This option represents a right to purchase a total of 86,467 shares of the Issuer's common stock, one quarter of which vested on April 16, 2019, with the remaining three quarters vesting in equal quarterly installments over the following three years. This option represents a right to purchase a total of 9,390 shares of the Issuer's common stock, one quarter of which vested on April 16, 2019, with the remaining three quarters vesting in equal quarterly installments over the following three years. This option represents a right to purchase a total of 36,367 shares of the Issuer's common stock, one quarter of which will vest on July 23, 2020, with the remaining three quarters vesting in equal quarterly installments over the following three years. Exhibit 24 - Power of Attorney /s/ Ryan A. Murr, Attorney-in-Fact for Michael R. Hayden 2019-11-08