X0206 3 2019-11-08 0 0001785173 89bio, Inc. ETNB 0001792018 Martins Ryan C/O 89BIO, INC. 535 MISSION STREET, 14TH FLOOR SAN FRANCISCO CA 94105 0 1 0 0 Chief Financial Officer Stock Option (Right to Buy) 3.11 2029-07-30 Common Stock 94901 D This option represents a right to purchase a total of 94,901 shares of the Issuer's common stock, one quarter of which will vest on July 21, 2020, with the remaining three quarters vesting in equal quarterly installments over the following three years. Exhibit 24 - Power of Attorney /s/ Ryan A. Murr, Attorney-in-Fact for Ryan Martins 2019-11-08