Segment Reporting

12 Months Ended

Dec. 31, 2024

Segment Reporting [Abstract]

Segment Reporting

13. Segment Reporting

Operating segments are defined as components of the entity for which separate financial information is made available and that is regularly evaluated by the chief operating decision maker (CODM) in making decisions regarding resource allocation and assessing performance. The Company's CODM is its chief executive officer and the Company manages its operations as a single segment for the purposes of assessing performance and making operating decisions. The Company is focused on the development of T cell receptor (TCR)-engineered T cell (TCR-T) therapies for the treatment of patients with cancer.

The CODM assesses the Company's performance by reviewing GAAP net loss and significant expenses by function along with the annual budget. The chief operating decision maker considers budget-to-actual variances on a quarterly basis when making decisions about the allocation of operating and capital resources.

The following table provides information about the Company's single operating segment which includes significant expenses by function along with significant non-cash expense items.

	Year Ended December 31,
	2024			2023
Revenue:
Collaboration and license revenue		2,816			21,049
Operating expenses:
Research and development:
Personnel expenses		31,742			24,165
Laboratory supplies, research materials and studies		31,468			30,101
Clinical studies		19,245			10,214
Facility-related and other		16,669			16,298
Stock-based compensation		4,846			2,876
Depreciation expense		3,380			4,499
General and administrative:
Personnel expenses		10,900			9,065
Legal and professional fees		7,380			7,119
Facility-related and other		6,576			6,976
Stock-based compensation		4,703			2,332
Depreciation Expense		728			862
Loss from operations		(134,821	)		(93,458	)
Other (expense) income:
Interest and other income, net		12,065			7,999
Interest expense		(3,653	)		(3,759	)
Loss on extinguishment of debt		(1,090	)		-
Net Loss		(127,499	)		(89,218	)