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Income Taxes - Reconciliation of the Federal Statutory Income Tax Rate to the Effective Tax Rate (Details)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Income Tax Disclosure [Abstract]    
Taxes at U.S. statutory rate 21.00% 21.00%
Changes from statutory rate:    
State taxes, net of federal benefit 8.30% 8.30%
Tax credits 5.10% 4.10%
Share-based compensation (0.90%) (1.00%)
Change in valuation allowance (33.80%) (32.40%)
Other 0.30% 0.00%
Effective income tax rate 0.00% 0.00%