Stock Based Compensation (Tables)

12 Months Ended

Dec. 31, 2022

Share-Based Payment Arrangement [Abstract]

Summary of Weighted-average for Each of The Assumptions The Company Used to Determine The Grant-date Fair Value of Options Granted

The weighted-average for each of the assumptions the Company used to determine the grant-date fair value of options granted were as follows:

	Year Ended December 31,
	2022			2021
Risk free interest rate		2.40	%		0.79	%
Expected term (in years)		6.24			6.05
Expected dividend yield		0	%		0	%
Expected volatility of underlying common stock		81	%		75	%

Summary of Stock Option Activity

The following table summarizes the stock option activity:

	Stock Options			Weighted Average Exercise Price		Weighted Average Remaining Life (in Years)		Intrinsic Value (in thousands)
Outstanding January 1, 2022		3,019,476		$	6.55		8.61	$	2,120
Granted		2,593,585			3.94
Exercised		(55,107	)		2.42
Canceled		(327,417	)		5.72
Outstanding December 31, 2022		5,230,537		$	5.35		8.49	$	—
Options vested or expected to vest as of December 31, 2022		5,230,537		$	5.35		8.49	$	—
Stock options exercisable as of December 31, 2022		1,550,423		$	5.56		7.39	$	—

Summary of Other Information Related to Option Activity

Other information related to the option activity for the years ended December 31, 2022 and 2021:

	Year Ended December 31,
	2022		2021
Weighted-average fair value of options granted	$	2.80	$	5.74
Intrinsic value of options exercised (in thousands)	$	62	$	1,174

Summary of Stock-based Compensation Expense

Stock-based compensation expense related to stock options and the stock purchase plan for the years ended December 31, 2022 and 2021 was classified in the consolidated statement of operations as follows (in thousands):

	Year Ended December 31,
	2022		2021
Research and development	$	1,626	$	878
General and administrative		2,925		1,638
Total stock-based compensation expense	$	4,551	$	2,516