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Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Cash flows from operating activities    
Net loss $ (71,395) $ (41,242)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 256 129
Stock-based compensation 8,055 1,391
Amortization of debt discount 698 544
Change in fair value of warrant liabilities 0 (95)
Other 540 0
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (includes the change in related party amounts of $82, and $0, respectively) 2,203 10,428
Accounts payable and accrued expenses (includes the change in related party amounts of $722 and $(181), respectively) (12,860) 8,129
Accrued clinical trial expenses (5,759)  
Accrued interest (10) 146
Operating right-of-use asset and lease liabilities 50 9
Other long-term assets 93 (200)
Net cash used in operating activities (78,129) (20,761)
Cash flows from investing activities    
Cash paid for property, plant and equipment (214) (733)
Net cash used in investing activities (214) (733)
Cash flows from financing activities    
Proceeds from issuance of common stock from exercise of stock options 516  
Net proceeds from issuance of long-term debt   25,000
Net cash provided by financing activities 516 25,000
Net (decrease) increase in cash and cash equivalents (77,827) 3,506
Cash and cash equivalents – beginning of period 287,496 243,765
Cash and cash equivalents – end of period 209,669 247,271
Supplemental disclosure of cash flow information    
Interest paid 1,833 1,309
Supplemental disclosure of noncash investing and financing activities    
Property and equipment purchases included in accounts payable and accrued liabilities 3 20
Final interest payment fee   2,063
Settlement of ESPP liability in common stock 358  
Settlement of 401(k) liability in common stock $ 323  
Operating lease liabilities arising from obtaining right-of-use assets   1,423
Conversion of Lender Warrants into equity   $ 318