X0306 4 2022-05-25 0 0001783183 Phathom Pharmaceuticals, Inc. PHAT 0001188940 COLA MICHAEL F C/O PHATHOM PHARMACEUTICALS, INC. 100 CAMPUS DRIVE, SUITE 102 FLORHAM PARK NJ 07932 1 0 0 0 Stock Option (Right to Buy) 7.40 2022-05-25 4 A 0 15000 0.00 A 2032-05-24 Common Stock 15000 15000 D The option was granted pursuant to the Issuer's Non-Employee Director Compensation Program. The option shall vest and/or become exercisable on the first to occur of (A) the first anniversary of the date of grant or (B) the next occurring annual meeting of the Issuer's stockholders, subject to Reporting Person's continuing in service on the Board through such vesting date. /s/ Larry Miller, Attorney-in-Fact for Michael F. Cola 2022-05-27