Stockholders' Equity (Tables)

12 Months Ended

Dec. 31, 2025

Summary of Common Stock Reserved for Future Issuance

Common stock reserved for future issuance consists of the following:

	December 31, 2025
Common stock warrants including pre-funded warrants		2,700,150
Stock options, performance stock units and restricted stock units outstanding		12,093,331
Shares available for issuance under the 2019 Incentive Plan		1,617,376
Shares available for issuance under the ESPP Plan		1,357,508
Shares available for issuance under the Inducement Plan		417,734
Balance at December 31, 2025		18,186,099

Summary of PSU Activity

The following table summarizes all PSU activity during the year ended December 31, 2025:

	Number of Stock Units			Weighted- Average Grant Date Fair Value Per Share
Unvested balance at January 1, 2025		—		$	—
Granted		1,189,893			6.56
Vested		(269,644	)		6.32
Forfeited		(425,125	)		5.76
Unvested balance at December 31, 2025		495,124		$	7.39

Summary of Weighted-Average Assumptions Used to Estimate Fair Value of Stock Options Granted and ESPP Awards

The weighted-average assumptions used to estimate the fair value of ESPP awards using the Black-Scholes option valuation model were as follows:

	Years Ended December 31,
	2025			2024
Assumptions:
Expected term (in years)		0.49			0.49
Expected volatility		112.83	%		105.23	%
Risk free interest rate		4.29	%		5.19	%
Dividend yield		—			—

Summary of Stock Option Activity

A summary of the Company’s stock option activity and related information is as follows during the year ended December 31, 2025:

	Options Outstanding			Weighted- Average Exercise Price		Weighted- Average Remaining Contractual Term		Aggregate Intrinsic Value (in thousands)
Balance at January 1, 2025		6,157,532		$	10.29		7.59	$	2,133
Options granted		4,823,636			5.53
Options exercised		(164,290	)		9.96
Options cancelled		(1,373,255	)		7.17
Balance at December 31, 2025		9,443,623		$	8.32		6.45	$	80,509
Options exercisable as of December 31, 2025		4,553,458		$	10.70		3.71	$	29,213
Vested and expected to vest as of December 31, 2025		9,443,623		$	8.32		6.45	$	80,509

Summary of Weighted-Average Assumptions Used to Estimate Fair Value of Stock Options

The weighted-average assumptions used to estimate the fair value of stock options using the Black-Scholes option valuation model were as follows:

	Years Ended December 31,
	2025			2024
Assumptions:
Expected term (in years)		6.07			6.04
Expected volatility		84.68	%		74.78	%
Risk free interest rate		4.06	%		4.14	%
Dividend yield		—			—

Summary of Stock-Based Compensation Expense

Stock-based compensation expense recognized for all equity awards has been reported in the statements of operations and comprehensive loss for the years ended December 31, 2025 and 2024 as follows (in thousands):

	Years Ended December 31,
	2025		2024
Research and development expense	$	6,864	$	5,567
Selling, general and administrative expense		21,855		18,480
Total	$	28,719	$	24,047

Restricted Stock Units (RSUs)

Summary of Unvested Shares

The following table summarizes RSU activity under the 2019 Plan during the year ended December 31, 2025:

	Number of Stock Units			Weighted- Average Grant Date Fair Value Per Share
Unvested balance at January 1, 2025		2,382,660		$	10.32
Granted		1,958,619			6.32
Vested		(1,482,618	)		10.88
Forfeited		(704,077	)		9.00
Unvested balance at December 31, 2025		2,154,584		$	6.73