Related Party Transactions - Additional Information (Details) - USD ($)		3 Months Ended		6 Months Ended
	May 05, 2020	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022	Dec. 31, 2022
Related Party Transaction [Line Items]
Outstanding accounts payable and accrued expenses		$ 27,000,000		$ 27,000,000		$ 15,000,000
Commercial Supply and Temporary Services Agreement
Related Party Transaction [Line Items]
Minimum purchase obligation		0		0
Commercial Supply Agreement
Related Party Transaction [Line Items]
Agreement extends period for termination	2 years
PCI Pharma Services | Related Party
Related Party Transaction [Line Items]
Expense related to services		14,000,000	$ 0	31,000,000	$ 0
PCI Pharma Services | Clinical Manufacturing Services
Related Party Transaction [Line Items]
Outstanding accounts payable and accrued expenses		1,300,000		1,300,000		1,100,000
PCI Pharma Services | Clinical Manufacturing Services | Related Party
Related Party Transaction [Line Items]
Expense related to services		200,000	100,000	300,000	400,000
Takeda | Commercial Supply and Temporary Services Agreement
Related Party Transaction [Line Items]
Outstanding accounts payable and accrued expenses		1,500,000		1,500,000		$ 1,400,000
Takeda | Related Party | Commercial Supply and Temporary Services Agreement
Related Party Transaction [Line Items]
Expense related to services		$ 100,000	$ 200,000	$ 100,000	$ 1,300,000