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Related Party Transactions - Additional Information (Details) - USD ($)
3 Months Ended
May 05, 2020
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
Related Party Transaction [Line Items]        
Outstanding accounts payable and accrued expenses   $ 17,000,000   $ 15,000,000
Commercial Supply and Temporary Services Agreement        
Related Party Transaction [Line Items]        
Minimum purchase obligation   0    
Commercial Supply Agreement        
Related Party Transaction [Line Items]        
Agreement extends period for termination 2 years      
PCI Pharma Services        
Related Party Transaction [Line Items]        
Expense related to services   3,000,000 $ 0  
PCI Pharma Services | Clinical Manufacturing Services        
Related Party Transaction [Line Items]        
Outstanding accounts payable and accrued expenses   1,200,000   1,100,000
Expense related to services   100,000 300,000  
Takeda | Commercial Supply and Temporary Services Agreement        
Related Party Transaction [Line Items]        
Outstanding accounts payable and accrued expenses   1,500,000   $ 1,400,000
Expense related to services   $ 100,000 $ 1,100,000