Statements of Stockholders' Equity (Deficit) - USD ($) $ in Thousands	Total	Common Stock	Treasury Stock	Additional Paid-in Capital	Accumulated Deficit
Beginning balance at Dec. 31, 2020	$ 194,271	$ 3		$ 579,755	$ (385,487)
Beginning balance, shares at Dec. 31, 2020		28,516,010
Issuance of common stock from exercise of stock options	1,944			1,944
Issuance of common stock from exercise of stock options, shares		107,583
Cashless exercise of common stock warrants		228,696
Cashless exercise of common stock warrants, shares			1
401(k) matching contribution	903			903
401(k) matching contribution, shares		26,750
Vesting of restricted shares, shares		1,601,950
Stock-based compensation	16,812			16,812
ESPP shares issued	819			819
ESPP shares issued, shares		30,237
Issuance of common stock warrants	1,290			1,290
Net loss	(143,883)				(143,883)
Ending balance at Dec. 31, 2021	$ 72,156	$ 3		601,523	(529,370)
Ending balance, shares at Dec. 31, 2021	30,511,226	30,511,226	1
Cashless exercise of common stock warrants		7,359,285
Cashless exercise of common stock warrants, shares			18
401(k) matching contribution	$ 1,116			1,116
401(k) matching contribution, shares		101,540
Vesting of restricted shares, shares		992,825
Issuance of common stock under ATM facility	24,595			24,595
Issuance of common stock under ATM facility, shares		2,414,897
Stock-based compensation	24,133			24,133
ESPP shares issued	909			909
ESPP shares issued, shares		89,098
Net loss	(197,723)				(197,723)
Ending balance at Dec. 31, 2022	$ (74,814)	$ 3		$ 652,276	$ (727,093)
Ending balance, shares at Dec. 31, 2022	41,468,871	41,468,871	19