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Income Taxes - Reconciliation Between Provision for Income Taxes and Income Taxes Computed Using U.S. Federal Statutory Corporate Tax Rate (Details) - USD ($)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Income Tax Disclosure [Abstract]    
Income taxes computed at the statutory rate $ (41,522,000) $ (30,216,000)
Permanent items 2,713,000 1,387,000
Research and development credit (2,453,000) (2,950,000)
Change in valuation allowance 41,137,000 31,783,000
Other 125,000 (4,000)
Provision (benefit) for income taxes $ 0 $ 0