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Stockholders' Equity - Additional Information (Details)
1 Months Ended 2 Months Ended 4 Months Ended 12 Months Ended
Dec. 16, 2020
USD ($)
$ / shares
shares
Oct. 29, 2019
USD ($)
$ / shares
shares
Sep. 30, 2022
USD ($)
shares
Jul. 31, 2022
shares
Jan. 31, 2022
shares
Aug. 31, 2021
shares
Nov. 30, 2020
USD ($)
Nov. 30, 2019
$ / shares
shares
Oct. 31, 2019
shares
May 31, 2019
shares
Mar. 31, 2019
shares
Feb. 27, 2023
USD ($)
shares
May 06, 2019
USD ($)
shares
Dec. 31, 2022
USD ($)
$ / shares
shares
Dec. 31, 2021
USD ($)
$ / shares
shares
Dec. 31, 2019
shares
Jan. 01, 2022
shares
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Preferred stock, shares authorized                           40,000,000 40,000,000    
Preferred stock, shares issued                           0 0    
Preferred stock, shares outstanding                           0 0    
Stock options, granted                           1,741,931      
Stock-based compensation cost | $                           $ 24,133,000 $ 16,812,000    
Common stock initially reserved for issuance                           8,678,288      
Unrecognized stock-based compensation expense | $                           $ 37,300,000      
Defined contribution plan employer contribution liabilities expense | $                           $ 1,300,000 $ 800,000    
Defined contribution plan, employer matching contribution, percentage                           75.00%      
Employer discretionary match number of shares settled       84,784 16,756 18,394                      
Unrecognized stock-based compensation expense, weighted-average period for recognition                           2 years 1 month 6 days      
Dividend yield                           0.00% 0.00%    
Stock Options                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Dividend yield                           0.00%      
Restricted Stock Units (RSUs)                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Unrecognized stock-based compensation expense | $                           $ 7,200,000      
Unrecognized stock-based compensation expense, weighted-average period for recognition                           1 year 9 months 18 days      
2019 Equity Incentive Plan                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Common stock, shares authorized for issuance                               2,231,739  
Number of shares available for issuance                 0                
Stock options, granted                               1,400,528  
2019 Equity Incentive Plan | Restricted Stock                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Stock awards, granted                               16,260  
2019 Incentive Award Plan                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Annual increase to shares available for issuance percentage of outstanding common stock                 5.00%                
Equity plan, description                           The number of shares initially available for issuance will be increased by (i) the number of shares subject to stock options or similar awards granted under the Existing Incentive Plan that expire or otherwise terminate without having been exercised in full after the effective date of the 2019 Plan and unvested shares issued pursuant to awards granted under the Existing Incentive Plan that are forfeited to or repurchased by the Company after the effective date of the 2019 Plan, with the maximum number of shares to be added to the 2019 Plan pursuant to clause (i) above or equal to 1,416,788 shares, and (ii) an annual increase on January 1 of each calendar year beginning in 2020 and ending in 2029, equal to the lesser of (a) 5% of the shares of common stock outstanding on the final day of the immediately preceding calendar year and (b) such smaller number of shares as determined by the board of directors. As of December 31, 2022, 957,885 shares remain available for issuance, which reflects 2,789,868 stock options and performance-based units, or PSU, and restricted stock unit, or RSU, awards granted, and 392,207 of awards cancelled or forfeited, during the year ended December 31, 2022 as well as an annual increases of 1,582,802 shares authorized on January 1, 2022.      
Number of shares remain available for issuance, annual increase                                 1,582,802
Common stock initially reserved for issuance                           957,885      
2019 Incentive Award Plan | Performance-Based Stock Units (PSU)                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Stock awards, granted                           37,500      
Stock-based compensation cost | $                           $ 0      
Unrecognized stock-based compensation expense | $                           $ 12,800,000      
2019 Incentive Award Plan | Restricted Stock Units (RSUs)                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Stock awards, granted                           1,010,437 1,010,437    
2019 Incentive Award Plan | Stock options, PSUs and RSUs                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Number of shares, granted                           2,789,868      
Number of shares, cancelled or forfeited                           392,207      
Employee Stock Purchase Plan                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Annual increase to shares available for issuance percentage of outstanding common stock                 1.00%                
Equity plan, description                           In addition, the number of shares available for issuance under the ESPP will be annually increased on January 1 of each calendar year beginning in 2020 and ending in 2029, by an amount equal to the lesser of: (i) 1% of the shares outstanding on the final day of the immediately preceding calendar year and (ii) such smaller number of shares as is determined by the board of directors. As of December 31, 2022, 752,938 shares of common stock remain available for issuance, which reflects 89,098 shares sold to employees during the year ended December 31, 2022.      
Stock-based compensation cost | $                           $ 500,000 $ 400,000    
Common stock initially reserved for issuance                 270,000         752,938      
Number of shares issued                           89,098      
Estimated weighted-average fair value | $ / shares                           $ 3.98 $ 14.66    
Unrecognized stock-based compensation expense | $                           $ 31,000      
Unrecognized stock-based compensation expense, weighted-average period for recognition                           6 months      
Dividend yield                           0.00% 0.00%    
Underwritten Public Offering                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Shares issued 2,250,000                                
Common stock, price per share | $ / shares $ 42.00                                
Proceeds from issuance initial public offering gross | $ $ 94,500,000                                
Purchase price per share after deducting underwriting discounts and commissions | $ / shares $ 39.48                                
Net proceeds after deducting underwriters commission | $ $ 88,800,000                                
Purchase of additional offering expenses | $ $ 200,000                                
At-the-Market Offering Program                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Shares issued     2,414,897                            
Proceeds from issuance of shares | $     $ 24,600,000                     $ 24,596,000      
Stock issuance costs | $     $ 800,000                            
Amount utilized of equity financing | $                           25,400,000      
Available equity financing amount | $                           $ 125,000,000.0      
At-the-Market Offering Program | Subsequent Event                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Shares issued                       1,514,219          
Proceeds from issuance of shares | $                       $ 14,500,000          
Employee and Nonemployee Director                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Estimated weighted-average fair value | $ / shares                           $ 8.40      
Open Market Sale Agreement with Jefferies LLC | At-the-Market Offering Program                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Sales commission payable as a percentage of sale of gross sales price per share             3.00%                    
Open Market Sale Agreement with Jefferies LLC | At-the-Market Offering Program | Maximum                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Aggregate offering price through equity financing | $             $ 125,000,000.0                    
Common Stock                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Shares issued                         2,524,852 2,414,897      
Number of shares authorized to repurchase                     3,373,408            
Stock repurchase program, number of shares right lapse                     843,352            
Remaining number of shares to be repurchased                     2,530,056            
Stock repurchase program, period in force                     48 months            
Stock repurchase program expiration period                     2023-03            
Proceeds from issuance of shares | $                         $ 1,000        
Repurchase right lapse each month after first anniversary, shares                         0.000208        
Repurchases of shares               17,560                  
Shares aggregate repurchase price | $ / shares               $ 5.20                  
Employer discretionary match number of shares settled                           101,540 26,750    
Common Stock | 2019 Incentive Award Plan                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Additional number of shares available for issuance                 1,416,788                
Common Stock | Employee Stock Purchase Plan                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Maximum percentage of eligible compensation contributed by participants                 20.00%                
Common Stock | IPO                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Shares issued   10,997,630                              
Common stock, price per share | $ / shares   $ 19.00                              
Proceeds from Initial Public Offering (IPO) | $   $ 191,500,000                              
Common Stock | Underwritten Public Offering                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Shares issued   1,434,473                              
Common Stock | Employees                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Remaining number of shares to be repurchased                           175,373      
Common Stock | First Anniversary                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Repurchase right lapse rate                         25.00%        
Common Stock | Takeda License                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Shares issued                   1,084,000              
Common Stock | Founders                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Remaining number of shares to be repurchased                           79,064      
Common Stock | Frazier                                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                  
Shares issued                     1,491,072