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Commitments and Contingencies - Additional Information (Details) - USD ($)
12 Months Ended
May 07, 2019
Dec. 31, 2022
Dec. 31, 2021
Commitments And Contingencies [Line Items]      
Common stock fair value   $ 3,000 $ 3,000
Common stock, shares issued   41,723,308 31,656,035
Common stock, authorized shares   400,000,000 400,000,000
Expenses incurred related to purchase commitments   $ 0 $ 0
Minimum      
Commitments And Contingencies [Line Items]      
Purchase obligation in the first 24-month period   $ 3,800,000  
Takeda License | Takeda      
Commitments And Contingencies [Line Items]      
License agreement description   The agreement will remain in effect, on a country-by-country and product-by-product basis, until the later of (i) the expiration of the last to expire valid patent claim covering vonoprazan fumarate alone or in combination with at least one other therapeutically active ingredient, (ii) the expiration of the applicable regulatory exclusivity and (iii) 15 years from the date of first commercial sale, unless earlier terminated. The Company may terminate the Takeda License upon six months’ written notice. The Company and Takeda may terminate the Takeda License in the case of the other party’s insolvency or material uncured breach. Takeda may terminate the Takeda License if the Company challenges, or assists in challenging, licensed patents  
Agreement expiration term from date of first commercial sale 15 years    
Cash consideration paid for license $ 25,000,000.0    
Common stock fair value $ 5,900,000    
Common stock, shares issued 1,084,000    
Warrants exercise price $ 0.00004613    
Initial fair value of warrants $ 47,900,000    
Additional warrant issued 0    
Maximum amount payable in sales milestones upon achievement of specified levels of product sales $ 250,000,000.0    
Warrants expiration date May 07, 2029    
Takeda License | Takeda | Common Stock      
Commitments And Contingencies [Line Items]      
Warrants issued to purchase shares 7,588,000